The Buffalo Bills entered week three of the NFL season as 17-point underdogs to the Minnesota Vikings. But that was the number of points the Bills scored in the first quarter of play, and with another 10 in the second and a scoreless Vikings team, and the game was all but over at halftime.

Buffalo Bills NFL odds Patriots line

Few fans saw the Buffalo Bills winning against the Minnesota Vikings, but those who did and put money on it received hefty payouts. (Image: John Autey/Pioneer Press)

The Bills went on to win 27-6, which marked the largest underdog upset since the Washington Redskins surprised the Dallas Cowboys 24-17 as 17.5-point long shots. ESPN’s David Purdum was first to report the historical upset data.

Purdum additionally reveals that William Hill took an $18,000 moneyline wager on the Vikings to beat the Bills at -1800 (1/18) odds. The gamble would have net just $1,000 should Minnesota have won. Instead, the person lost it all.

The Westgate SuperBook said it took a $9,000 bet on the Vikings at -2000 (1/20) odds. That would have net just $900.

Bills Pay Some Bills

Buffalo’s first win of the season, which came on the road in Minnesota, delivered big paydays for a few fortunate gamblers.

The South Point says two $1,000 moneyline bets on the Bills at 12/1 and 11/1 odds respectively won $12,000 and $11,000. William Hill printed a $1,000 bet on 10/1 odds on the Bills that cost the house $10,000.

The Bills and Vikings matchup wasn’t the only week three game attracting a flurry of action in Las Vegas.

MGM Resorts says one bettor placed multiple six-figure wagers on the Saints to cover and on the moneyline. They did both in a 43-37 overtime victory against the Atlanta Falcons. MGM says the game was its largest loss to date in the 2018 NFL season.

Pats Helps House

Las Vegas sportsbooks had a disappointing Sunday, and several were looking at losses ahead of Sunday Night Football between the New England Favorites and Detroit Lions. The Pats were seven-point favorites, but the Detroit defense managed to keep Tom Brady and company in check.

Up 13-3 at halftime, the Lions went on to win comfortably 26-10 to upset the Pats. The books said much more money was on the Patriots than the Lions. MGM stated it had eight times more cash on New England than Detroit, and Caesars Palace reported 86 percent of its slips printed were on the favorite.

Purdum tweeted ahead of the SNF game, “A Patriots’ cover against the Lions would seal the first losing Sunday of the NFL season for multiple Las Vegas sportsbooks.”

Despite a 1-2 start, the Patriots are still heavily favored in week four when they return home to Foxborough to play the 3-0 Miami Dolphins. The SuperBook opened the line with the Pats spotting the visitors 9.5 points.

The largest week four opening spread is again the Bills (1-2), who are being given 10.5 points when they travel to Lambeau to play the Green Bay Packers (1-1-1). The favorites are coming off an embarrassing 31-17 loss to the Washington Redskins in a game where Aaron Rodgers’ squad were 2.5-point favorites.