Villanova comes into the Final Four of the NCAA Tournament as the favorite to cut down the nets in San Antonio. But three other teams still stand in their way, including one of the most unlikely championship contenders in recent memory.

Final Four NCAA Tournament

The Villanova Wildcats are seeking their second national title in three years, but will have to first contend with Kansas, Michigan, and Loyola-Chicago in the Final Four. (Image: Maddie Meyer/Getty)

Villanova (34-4) has been on the radar of college basketball fans all season long. The 2016 national champions were picked by many to go all the way even before the tournament began, and now they are just two games away from winning the schools third ever national title in men’s basketball.

No. 1 Seeds Battle for Spot in Final

Standing in their way in the Final Four is fellow No. 1 seed Kansas (31-7). The Jayhawks have felt somewhat overlooked by pundits, as few picked them to survive a loaded Midwest region and reach the Final Four. But Kansas isn’t satisfied simply with making it to the final weekend of the tournament.

“We’ve got a ton of work [to do],” said Kansas coach Bill Self. “Even though you say you’re so close, we’re still light years away from doing what we want to do.”

Villanova has comfortably won their first four games in the tournament, but they don’t expect things to be so easy the rest of the way. Wildcats coach Jay Wright noted that based on what he’s heard from other coaches, his team might be looking in the mirror when they go up against Kansas.

“I heard Bob Huggins say that we remind them of Kansas. I heard Chris Beard say we remind them of Kansas,” Wright said. “I always took that as a compliment, and now we’ve got to play against them, so now I’m not so excited about it.”

At bwin, Villanova has been posted as a 5.5-point favorite in their semifinal matchup. That’s the same line found in the other game, where Michigan is giving 5.5 points to the upstart Loyola-Chicago Ramblers.

Ramblers Looking to Complete Miracle Run

Loyola-Chicago (32-5) has captured the attention of the country by coming from out of nowhere as a No. 11 seed to reach the Final Four. The Ramblers won their first three games by a combined four points, but it would be wrong to call them lucky: while they were unknown heading into the tournament, they have gotten this far based on strong guard play and tough defense.

They’ve also captured America’s hearts, with more than a little help from Sister Jean Dolores Schmidt, the 98-year-old nun who has become the face of the Ramblers.

“This is the most fun I’ve had in my life,” Sister Jean said at her own March Madness press conference. “And I almost didn’t get here, but I fought hard enough to do that because I wanted to be with the guys.”

Even Michigan coach John Beilein acknowledged that the Loyola-Chicago story is hard to root against.

“If I wasn’t coaching Michigan, I’d probably be rooting for them too,” Beilein said.

While Michigan is the favorite to knock off the Ramblers, they would likely be an underdog against either opponent they would then meet in the national championship game.

At Ladbrokes, Villanova is an even money favorite to win the national title, followed by Michigan (5/2), Kansas (3/1) and Loyola-Chicago (12/1).